Сучасний погляд практичного лікаря на патогенез ураження нирок при прееклампсії
DOI:
https://doi.org/10.15574/HW.2016.111.67Ключові слова:
прееклампсія, гломерулярне ураження, артеріальна гіпертензія, васкулоендотеліальний фактор росту (VEGF), розчинна fms-подібна тирозинкіназа-1 (sFlt-1)Анотація
У статті представлені сучасні дані про патогенез ниркового ураження при прееклампсії (ПЕ), вплив дисбалансу системи sFlt-1/анти-VEGF на клінічні симптоми нефропатії при ПЕ. Однак незважаючи на високий інтерес акушерів і нефрологів до проблеми ПЕ на сьогодні даних про вплив ПЕ на ниркове ураження у значенні передбачення термінів розвитку ПЕ вкрай недостатньо – тому необхідні подальші дослідження щодо цієї теми.
Ключові слова: прееклампсія, гломерулярне ураження, артеріальна гіпертензія, васкулоендотеліальний фактор росту (VEGF), розчинна fms-подібна тирозинкіназа-1 (sFlt-1).
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