Профілактична сальпінгектомія – необхідність чи варіант норми?

Автор(и)

  • Р. N. Veropotvelyan ОКЗ «Міжобласний центр медичної генетики і пренатальної діагностики», м. Кривий Ріг,
  • I. S. Tsehmistrenko Перинатальний центр, м. Київ,
  • N. P. Veropotvelyan ОКЗ «Міжобласний центр медичної генетики і пренатальної діагностики», м. Кривий Ріг,
  • N. V. Volenko ОКЗ «Міжобласний центр медичної генетики і пренатальної діагностики», м. Кривий Ріг,

DOI:

https://doi.org/10.15574/99905

Ключові слова:

гістеректомія, сальпінгектомія, рак яєчників, оваріальний резерв

Анотація

У статті показана необхідність проведення симультанної сальпінгектомії пацієнткам під час гістеректомії. За даними аналізу публікацій описано наукове обґрунтування операції при різному ступені ризику розвитку серозного раку яєчників. Дискутується роль методу у підвищенні ефективності лікування безплідності. Аналіз літературних даних свідчить, що після сальпінгектомії може сформуватися вторинна недостатність яєчників. Це закономірно пояснюється негативними наслідками дефіциту естрогенів, які можуть перевищувати користь від зниження захворюваності на рак яєчників та профілактики запальних захворювань органів малого таза.


Ключові слова:
гістеректомія, сальпінгектомія, рак яєчників, оваріальний резерв.

Посилання

Matorras R, Rabanal A, Prieto B, Diez S, Brouard I, Mendoza R et al. 2013. Hysteroscopic hydrosalpinx occlusion with Essure device in IVF patients when salpingectomy or laparoscopy is contraindicated. Eur. J. Obstet. Gynecol. Reprod. Biol. 169(1):54–9. http://dx.doi.org/10.1016/j.ejogrb.2013.02.008; PMid:23561020

Findley AD, Siedhoff MT, Hobbs KA, Steege JF, Carey ET, McCall CA et al. 2013. Short-term effects of salpingectomy during laparoscopic hysterectomy on ovarian reserve: a pilot randomized controlled trial. Fertil. Steril. 100(6):1704–8. http://dx.doi.org/10.1016/j.fertnstert.2013.07.1997

Hill MJ, Cooper JC, Levy G, Alford C, Richter KS, DeCherney AH et al. 2014. Ovarian reserve and subsequent assisted reproduction outcomes after methotrexate therapy for ectopic pregnancy or pregnancy of unknown location. Fertil. Steril. 101(2):413–9. http://dx.doi.org/10.1016/j.fertnstert.2013.10.027; PMid:24269042 PMCid:PMC3946660

Uyar I, Yucel OU, Gezer C, Gulhan I, Karis B, Hanhan HM et al. 2013. Effect of single-dose methotrexate on ovarian reserve in women with ectopic pregnancy. Fertil. Steril. 100(5):1310-3. http://dx.doi.org/10.1016/j.fertnstert.2013.06.040; PMid:23891021

Wiser A, Gilbert A, Nahum R, Orvieto R, Haas J, Hourvitz A et al. 2013. Effects of treatment of ectopic pregnancy with methotrexate or salpingectomy in the subsequent IVF cycle. Reprod. Biomed. Online. 26(5):449–53. http://dx.doi.org/10.1016/j.rbmo.2013.01.018; PMid:23518030

Xi W, Gong F, Tang Y, Zhang H, Lu G. 2012. Ovarian response to gonadotropins after laparoscopic salpingectomy for ectopic pregnancy. Int. J. Gynaecol. Obstet. 116(2):93–6. http://dx.doi.org/10.1016/j.ijgo.2011.10.009; PMid:22103980

Yi QH, Ling SR, Chen KM, He WR, Li L, Yi CJ. 2012. Evaluation of the clinical value of simultaneous hysterectomy and bilateral salpingectomy in perimenopausal women. Zhonghua Fu Chan Ke Za Zhi. 47(2):110–4. PMid:22455742

Meng XH, Zhu YM. 2006. Effect of salpingectomy on ovarian function. Zhejiang Da Xue Xue Bao Yi Xue Ban. 35(5):555–9. PMid:17063552

Ni L, Sadiq S, Mao Y, Cui Y, Wang W, Liu J. 2013. Influence of various tubal surgeries to serum antimullerian hormone level and outcome of the subsequent IVF-ET treatment. Gynecol. Endocrinol. 29(4):345–9. http://dx.doi.org/10.3109/09513590.2012.743004; PMid:23339657

Sezik M, Ozkaya O, Demir F, Sezik HT, Kaya HJ. 2007. Total salpingectomy during abdominal hysterectomy: effects on ovarian reserve and ovarian stromal blood flow. J. Obstet. Gynaecol. Res. 33(6):863–9. http://dx.doi.org/10.1111/j.1447-0756.2007.00669.x

Petrov IA, Tihonovskaya OA, Okorokov AO, Kupriyanova II, Fateeva AS, Petrova MS, Logvinov SV. 2016. Prophylactic salpingectomy. Obstetrics and gynecology 2:36–42. http://dx.doi.org/10.18565/aig.2016.2.36-42

Ulug P, Oner G. 2014. Evaluation of the effects of single or multiple dose methotrexate administration, salpingectomy on ovarian reserve of rat with the measurement of anti-Mьllerian hormone (AMH) levels and histological analysis. Eur. J. Obstet. Gynecol. Reprod. Biol. 181:205–9. http://dx.doi.org/10.1016/j.ejogrb.2014.07.011; PMid:25171264

Dobrokhotova JE, Boyar AE, Haidar LA et al. 2009. Clinical lectures on obstetrics and gynecology. Moscow, GEOTAR-Media:312.

Strizhakov AN, Davydov AI, Musayev RD. 2011. Ovarian reserve in patients with endometrioid ovarian cysts after laparoscopic surgery using a surgical high energies. In the book: GT Sukhikh, LV Adamyan. New technologies in the diagnosis and treatment of gynecological diseases. M:101–2.

Iwase A, Nakamura T, Nakahara T, Goto M, Kikkawa F. 2014. Assessment of ovarian reserve using anti-Mьllerian hormone levels in benign gynecologic conditions and surgical interventions: a systematic narrative review. Reprod. Biol. Endocrinol. 12:125. http://dx.doi.org/10.1186/1477-7827-12-125; PMid:25510324 PMCid:PMC4274680

Mukhopadhaya N, Manyonda IT. 2013. The hysterectomy story in the United Kingdom. Midlife Health 4(1):40–1. http://dx.doi.org/10.4103/0976-7800.109635

Schenberg T, Mitchell G. 2014. Prophylactic bilateral salpingectomy as a prevention strategy in women at high-risk of ovarian cancer: a mini-review. Front. Oncol. 4:21. http://dx.doi.org/10.3389/fonc.2014.00021; PMid:24575389 PMCid:PMC3918654

Vorwergk J, Radosa MP, Nicolaus K, Baus N, Jimenez Cruz J, Rengsberger M et al. 2014. Prophylactic bilateral salpingectomy (PBS) to reduce ovarian cancer risk incorporated in standard premenopausal hysterectomy: complications and re-operation rate. J. Cancer Res. Clin. Oncol. 140(5):859–65. http://dx.doi.org/10.1007/s00432-014-1622-6; PMid:24573653

Chan CC, Ng EH, Ho PC. 2005. Ovarian changes after abdominal hysterectomy for benign conditions. J. Soc. Gynecol. Investig. 12(1):54–7. http://dx.doi.org/10.1016/j.jsgi.2004.07.004; PMid:15629673

Nahбs EA, Pontes A, Traiman P, Nahбs-Neto J, Dalben I, De Luca L. 2003. Inhibin B and ovarian function after total abdominal hysterectomy in women of reproductive age. Gynecol. Endocrinol. 17(2):125–31. http://dx.doi.org/10.1080/713603218; http://dx.doi.org/10.1080/gye.17.2.125.131; PMid:12737673

Vuorento T, Mдenpдд J, Huhtaniemi I. 1992. Follow-up of ovarian endocrine function in premenopausal women after hysterectomy by daily measurements of salivary progesterone. Clin. Endocrinol. (Oxf). 36(5):505–10. http://dx.doi.org/10.1111/j.1365-2265.1992.tb02253.x

Chalmers C, Lindsay M, Usher D, Warner P, Evans D, Ferguson M. 2002. Hysterectomy and ovarian function: levels of follicle stimulating hormone and incidence of menopausal symptoms are not affected by hysterectomy in women under age 45 years. Climacteric. 5(4):366–73. http://dx.doi.org/10.1080/cmt.5.4.366.373; http://dx.doi.org/10.1080/713605316; PMid:12626216

Ciarmela P, Islam MS, Reis FM, Gray PC, Bloise E, Petraglia F et al. 2011. Growth factors and myometrium: biological effects in uterine fibroid and possible clinical implications. Hum. Reprod. Update. 17(6):772–90. http://dx.doi.org/10.1093/humupd/dmr031

Nahбs EA, Pontes A, Nahбs-Neto J, Borges VT, Dias R, Traiman P. 2005. Effect of total abdominal hysterectomy on ovarian blood supply in women of reproductive age. J. Ultrasound Med. 24(2):169–74.

Bhattacharya S, Mollison J, Pinion S, Parkin DE, Abramovich DR, Terry P et al. 1996. A comparison of bladder and ovarian function two years following hysterectomy or endometrial ablation. Br. J. Obstet. Gynaecol. 103(9):898–903. http://dx.doi.org/10.1111/j.1471-0528.1996.tb09909.x; PMid:8813310

Aylamazyan E. 2004. Gynecology from puberty to menopause. M:409.

Morelli M, Venturella R, Mocciaro R, Di Cello A, Rania E, Lico D et al. 2013. Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere. Gynecol. Oncol. 129(3):448–51. http://dx.doi.org/10.1016/j.ygyno.2013.03.023

Colgan TJ, Murphy J, Cole DE, Narod S, Rosen B. 2001. Occult carcinoma in prophylactic oophorectomy specimens: prevalence and association with BRCA germline mutation status. Am. J. Surg. Pathol. 25(10):1283–9. http://dx.doi.org/10.1097/00000478-200110000-00009

Piek JM, van Diest PJ, Zweemer RP, Jansen JW, Poort-Keesom RJ, Menko FH et al. 2001. Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer. J. Pathol. 195(4):451–6. http://dx.doi.org/10.1002/path.1000; PMid:11745677

Crum CP, Drapkin R, Kindelberger D, Medeiros F, Miron A, Lee Y. 2007. Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer. Clin. Med. Res. 5(1):35–44. http://dx.doi.org/10.3121/cmr.2007.702

Salvador S, Gilks B, Kцbel M, Huntsman D, Rosen B, Miller D. 2009. The fallopian tube: primary site of most pelvic high-grade serous carcinomas. Int. J. Gynecol. Cancer. 19(1):58–64. http://dx.doi.org/10.1111/igc.0b013e318199009c

Leblanc E, Narducci F, Farre I, Peyrat JP, Taieb S, Adenis C et al. 2011. Radical fimbriectomy: a reasonable temporary risk-reducing surgery for selected women with a germ line mutation of BRCA 1 or 2 genes? Rationale and preliminary development. Gynecol. Oncol. 121(3):472–6. http://dx.doi.org/10.1016/j.ygyno.2011.02.012

Greene MH, Mai PL, Schwartz PE. 2011. Does bilateral salpingectomy with ovarian retention warrant consideration as a temporary bridge to risk-reducing bilateral oophorectomy in BRCA1/2 mutation carriers? Am. J. Obstet. Gynecol. 204(1):19.e1-6. http://dx.doi.org/10.1016/j.ajog.2010.05.038; PMid:20619389 PMCid:PMC3138129

Repasy I, Lendvai V, Koppan A, Bodis J, Koppan M. 2009. Effect of the removal of the Fallopian tube during hysterectomy on ovarian survival: the orphan ovary syndrome. Eur. J. Obstet. Gynecol. Reprod. Biol. 144(1):64–7. http://dx.doi.org/10.1016/j.ejogrb.2008.12.019; PMid:19261370

Morse AN, Schroeder CB, Magrina JF, Webb MJ, Wollan PC, Yawn BP. 2006. The risk of hydrosalpinx formation and adnexectomy following tubal ligation and subsequent hysterectomy: a historical cohort study. Am. J. Obstet. Gynecol. 194(5):1273–6. http://dx.doi.org/10.1016/j.ajog.2005.11.014; PMid:16579950

Ghezzi F, Cromi A, Siesto G, Bergamini V, Zefiro F, Bolis P. 2009. Infectious morbidity after total laparoscopic hysterectomy: does concomitant salpingectomy make a difference? BJOG. 116(4):589–93. http://dx.doi.org/10.1111/j.1471-0528.2008.02085.x

Ouldamer L, Caille A, Body G. 2013. Fallopian tube prolapse after hysterectomy: a systematic review. PLoS One. 8(10):e76543. http://dx.doi.org/10.1371/journal.pone.0076543; PMid:24116117 PMCid:PMC3792027

Parihar M, Mirge A, Hasabe R. 2009. Hydrosalpinx functional surgery or salpingectomy? The importance of hydrosalpinx fluid in assisted reproductive technologies. J. Gynecol. Endosc. Surg. 1(1):12–6. http://dx.doi.org/10.4103/0974-1216.51903; PMid:22442504 PMCid:PMC3304258

Dechaud H, Hedon B. 2000. What effect does hydrosalpinx have on assisted reproduction? The role of salpingectomy remains controversial. Hum. Reprod. 15(2):234–5. http://dx.doi.org/10.1093/humrep/15.2.234; PMid:10655289

Strandell A, Lindhard A, Waldenstrцm U, Thorburn J, Janson PO, Hamberger L. 1999. Hydrosalpinx and IVF outcome: a prospective, randomized multicentre trial in Scandinavia on salpingectomy prior to IVF. Hum. Reprod. 14(11):2762–9. http://dx.doi.org/10.1093/humrep/14.11.2762

Johnson NP, van Voorst S, Sowter MC, Strandell A, Mol BW. 2010. Surgical treatment for tubal disease in women due to undergo in vitro fertilization. Cochrane Database Syst. Rev. (1):CD002125. PMid:20091531

Bontis JN, Theodoridis TD. 2006. Laparoscopic management of hydrosalpinx. Ann. N.Y. Acad. Sci. 1092:199–210. http://dx.doi.org/10.1196/annals.1365.017; PMid:17308145

Strandell A, Lindhard A. 2002. Why does hydrosalpinx reduce fertility? The importance of hydrosalpinx fluid. Hum. Reprod. 17(5):1141–5. http://dx.doi.org/10.1093/humrep/17.5.1141; PMid:11980729

Atilgan R, Kuloрlu T, Boztosun A, Orak U, Baspinar M, Can B et al. 2015. Investigation of the effects of unilateral total salpingectomy on ovarian proliferating cell nuclear antigen and follicular reserve: experimental study. Eur. J. Obstet. Gynecol. Reprod. Biol. 188(1):56–60. http://dx.doi.org/10.1016/j.ejogrb.2015.02.028; PMid:25790915

Gelbaya TA, Nardo LG, Fitzgerald CT, Horne G, Brison DR, Lieberman BA. 2006. Ovarian response to gonadotropins after laparoscopic salpingectomy or the division of fallopian tubes for hydrosalpinges. Fertil. Steril. 85(5):1464–8. http://dx.doi.org/10.1016/j.fertnstert.2005.10.036; PMid:16580673

Grynnerup AG, Lindhard A, Sшrensen S. 2013. Anti-Mьllerian hormone levels in salpingectomized compared with nonsalpingectomized women with tubal factor infertility and women with unexplained infertility. Acta Obstet. Gynecol. Scand. 92(11):1297–303. http://dx.doi.org/10.1111/aogs.12234; PMid:24032634

Nakagawa K, Ohgi S, Nakashima A, Horikawa T, Irahara M, Saito HJ. 2008. Laparoscopic proximal tubal division can preserve ovarian reserve for infertility patients with hydrosalpinges. J. Obstet. Gynaecol. Res. 34(6):1037–42. http://dx.doi.org/10.1111/j.1447-0756.2008.00801.x

Ye XP, Yang YZ, Sun XX. 2015. A retrospective analysis of the effect of salpingectomy on serum anti-Mьllerian hormone level and ovarian reserve. Am. J. Obstet. Gynecol. 212(1);53:1-10.

Ashrafyan LA. 2014. Systematic errors in the therapeutic approaches for ovarian cancer. Practical oncology. Practical Oncology 15:4.

Kochetkova EO, Degemerzanova NK. 2013, iyul-avgust. Risk razvitiya raka molochnoy zhelezyi i yaichnikov, obuslovlennyiy mutatsiyami genov BRCA1, BRCA2, CHEK2. Kazahstanskiy Meditsinskiy Zhurnal:4(34).

##submission.downloads##

Номер

Розділ

Актуальні теми