Плацента як дзеркало вагітності (Огляд літератури)
DOI:
https://doi.org/10.15574/HW.2019.139.101Ключові слова:
вагітність, невиношування, плацента, апоптоз, проліферація, CD45, інтерлейкін-22, натуральні кілери (CD56/NCAM-1), TNF-a, фактори росту (VEGF, PIBF, PDGF, PIGF, TGF-)Анотація
Плацента є органом біологічного моніторингу, дзеркалом вагітності, предиктором здоров’я. Успішна імплантація – запорука формування здорової плаценти та, отже, здорового майбутнього покоління. Порушення процесів апоптозу, проліферації у трофобласті, стромальних і ендотеліальних клітинах ворсинчастого хоріона, децидуальній та плодовій оболонках призводять до змін плацентарно-плодових взаємовідносин, а у подальшому – до формування патології. Вивчення плацентарних маркерів невиношування вагітності є новим поглядом на діагностику та перспективним напрямком попередження репродуктивних втрат.
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