Сучасний погляд на великі акушерські синдроми (Огляд іноземної літератури)
DOI:
https://doi.org/10.15574/HW.2019.138.96Ключові слова:
великі акушерські синдроми, дефективна глибока плацентація, децидуально-міометріальний інтерфейс, спіральні артерії, оксидативний стрес, децидуальні імунні клітини, преімплантаційний фактор, прогестерон-індукований блокувальний фактор, прогестерон, дидрогестеронАнотація
У статті представлено огляд літератури з питань етіології, патогенезу і можливих методів профілактики великих акушерських синдромів. Показано, що у їхній основі лежить дефективна глибока плацентація внаслідок відсутності, часткової трансформації, а також обструкції спіральних артерій децидуально-міометріального інтерфейсу, зумовлена гормональними причинами. Перспективним напрямом профілактики розвитку великих акушерських синдромів є застосування препаратів, що можуть справляти модулювальний ефект на зазначені фактори.
Посилання
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